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Intracytoplasmic Sperm Injection ICSI

Intracytoplasmic sperm injection (ICSI) provides new hope for couples with moderate to severe male factor infertility In the past, the only option for these couples was to use sperm from a donor. This meant the child had genes from the natural mother but not the father.

ICSI is performed as a part of an IVF cycle and involves placement of a single sperm directly into the egg. The sperm can be obtained from and ejaculate, or in the case of severe male factor infertility, directly from the male reproductive tract. Eggs are delicate and embryologists use sophisticated micromanipulation equipment and microscopic needles to pierce the egg and insert the sperm.

ICSI is sometimes employed when the cause of infertility is unknown, when the female is older, or after failed IVF cycles without ICSI. Approximately 47% of IVF cycles in the United States included ICSI in the year 2000.

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